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U.Okay. Tackles Giant Vaccine Rollout After Botched Covid Response

LONDON — In Bristol, a sports stadium is being converted into a temporary clinic to provide inoculations, as is a racecourse outside London. Village halls, libraries and parking lots across the country are also being quickly turned into makeshift vaccination centers, with the government enlisting military planners for advice.

As it prepares to begin rolling out a coronavirus vaccine on Tuesday, Britain is taking on the biggest logistical challenge ever faced by the country’s health service, the vaccination of tens of millions of people against coronavirus in a matter of months. At the same time, law enforcement authorities are contending with an array of potential security threats to the vaccination campaign.

Inoculations are expected to begin Tuesday at selected hospitals throughout Britain that have received the first batches of vaccine made by Pfizer and BioNTech, which need to be stored at very low temperatures. But the temporary clinics that are being hurriedly put together are expected to play critical roles as the mass vaccination program expands.

Retired health workers are being asked to help, while the National Health Service is also recruiting tens of thousands of first aid workers and others to help administer the shot, as the vaccine becomes available to progressively more people.

“I think all people who can help should put their hands up,” said Sarah Wollaston, who worked as a doctor before serving in Parliament until recently. She has just completed part of an online refresher course, to qualify to help in the vaccine rollout.

“Physically, giving someone a vaccine is very straightforward,” she said. “The challenge is the logistics.”

While industry experts and health officials grapple with that, law enforcement officers and cyber-sleuths face an equally pressing challenge in the potential security threats surrounding a product in such high demand.

“It is the most valuable asset on earth right now,” said Lisa Forte, a former British counterintelligence employee and a partner at Red Goat, a cybersecurity firm. “Naturally, this will attract highly skilled cybercriminals, criminal groups and state actors.”

Europol has warned that organized crime groups might target trucks containing vaccines for theft and hijacking, and last week Interpol warned against an “onslaught of all types of criminal activity linked to the COVID-19 vaccine,” which it has described as “liquid gold.”

From the factory to hospitals and other sites, the Pfizer vaccine — because it has to be stored at around minus 70 degrees Celsius, or minus 94 Fahrenheit — is acutely vulnerable to sabotage, in addition to theft.

“With the vaccine, the two biggest risks are maintaining the cold chain and interception by public or private actors,” said Sarah Rathke, a lawyer at Squire Patton Boggs who specializes in supply chain litigation.

“It may be the most difficult supply chain challenge posed in recent history, with not a lot of time to prepare for it,” Ms. Rathke added.

Cyberattacks can reveal a wealth of information about the vaccines that can be exploited by state actors and criminal gangs, experts say.

Last week, IBM said it had detected a series of cyberattacks in September against companies involved in the distribution of coronavirus vaccines across the world. IBM said the attackers, whose identity could not be determined, had tried to learn how the vaccines would be stored and delivered.

“We’ve seen petrochemical companies targeted, because they’re essential in producing dry ice used to store the vaccine,” said Claire Zaboeva, a senior cyber-threat analyst at IBM’s Security X-Force.

As nations compete to be among the first to administer the vaccine, Ms. Zaboeva added, state actors or even terrorist groups might try to disrupt deliveries. “Making loads of vaccine doses spoiled and useless, that would be a pretty destructive attack,” she said.

While security agencies look after those concerns, Britain’s health service will have the daunting problem of managing a mass vaccination program that will reach further and faster into the population than any other public health outreach in living memory.

One charity, St. John Ambulance, aims to help train up to 30,000 vaccinators and others to help at inoculation centers.

“Rolling out a vaccine to tens of millions of people will be a monumental task as we look to save lives and hopefully bring about an eventual return to our normal way of life,” said Ian Hudspeth, Chairman of the Community Wellbeing Board for the Local Government Association, which represents local municipalities.

Success is hardly guaranteed, given Britain’s spotty record on logistics during the Covid-19 crisis. In the early stages of the pandemic hospitals were left chronically short of basic protective equipment like masks and gloves, putting some workers at risk of infection.

Since then, the government has struggled to establish a test and trace system, despite budgeting around $16 billion for the much-criticized project.

Already, Pfizer’s problems sourcing raw materials may force it to cut the number of vaccine doses promised for delivery this year to Britain possibly by around half, to five million. And there is a potential bottleneck in the production of dry ice needed for packing and shipping the vaccine.

Yet experts are cautiously optimistic that the vaccine rollout will go better than the government’s earlier, fumbling efforts to address the pandemic because it will be handled under the umbrella of the National Health Service, which has extensive experience with organizing mass immunizations, like annual flu shots.

“It is not going to be without problems because of its scale and the logistics — I would be amazed if, in six months something, somewhere, didn’t go wrong,” said Helen Buckingham, director of strategy and operations at the Nuffield Trust, a research institute specializing in health.

But the concept of mass vaccination is a familiar one, she added, “and overall people are putting a lot of effort into making this work.”

Vaccines will be offered at three different types of locations: hospitals; doctors’ offices and clinics; and temporary vaccination centers still being prepared, including drive-through sites, sports stadiums and public buildings. Family doctors, who will carry much of the burden, can call on their experience of giving at least 15 million flu shots each year.

Coronavirus vaccination will be different for several reasons, however. In addition to the Pfizer and BioNTech vaccine, Britain is likely to authorize at least two others, one produced by Moderna and another by AstraZeneca and the University of Oxford. But when and where each one will be available is unclear.

Martin Marshall, chair of the council of the Royal College of General Practitioners, notes that refrigeration requirements particularly for the Pfizer and Moderna vaccines introduce a complication doctors do not have to manage with flu shots. Both require a second injection after several weeks, which can be an administrative nightmare.

“We are pretty used to delivering big vaccination programs, but of course no one has ever had to deliver one in a situation where the vaccinations don’t come through in pre-filled syringes,” said Mr. Marshall.

Doctors’ offices and other temporary clinics might come more into play, experts say, if the AstraZeneca vaccine gains approval. In addition to costing far less, it can be stored at normal refrigeration levels.

Then there are worries that average Britons, not to speak of anti-vaccination campaigners, will be reluctant to take the Pfizer and Moderna vaccines, which rely on a relatively untested technology.

Priority will go to those at highest risk and the oldest Britons, so a system will also be needed to call the right people in for appointments at specified times, then to do so again three weeks later for the second shot.

Early plans to vaccinate nursing home residents have been shelved because of the deceptively vexing issue of how to break down the 975-dose batches that Pfizer ships and safely take them into those facilities. And it is unclear when — and in what quantity — other vaccines will become available.

All this has to be done at a time when the health care sector is under acute strain, its staff stretched after months of relentless pressure and during a winter season when people are generally more susceptible to illness.

Nonetheless, Mr. Marshall is confident that the vaccine rollout can succeed.

“I think we can make this work if we work across the N.H.S. and show some flexibility,” he said. “It plays to the strength of the N.H.S., which is a centralized, organized and managed system — and it plays to our values as well.”

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